PKN1 anticorps

N° du produit ABIN6566611

Cet anticorps Lapin Polyclonal détecte spécifiquement PKN1 dans WB et IHC. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour PKN1 anticorps (ABIN6566611)

Antigène: PKN1 (Protein Kinase N1 (PKN1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKN1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PKN1 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human PKN1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:1000 IHC 1:50 - 1:100

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PKN1

Antigène: PKN1 (Protein Kinase N1 (PKN1))

Autre désignation: PKN1

Sujet:

Synonyms: DBK,DPKN,PAK 1,PRK 1,PROTEIN KINASE C RELATED KINASE 1,SERINE/THREONINE PROTEIN KINASE N

Background: The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Poids moléculaire:

Observed_MW: 120kDa

Calculated_MW: 104kDa

ID gène: 5585

UniProt: Q16512